The Project: ALIVER is a project that has received funding from the European Union’s Horizon 2020 research and innovation programme after 25 years of experimental research and data collection on extracorporeal perfusion as a therapy option in liver failure. The ALIVER Consortium has developed and optimised a novel ‘liver dialysis device’, DIALIVE.
The Challenge: The incidence of liver disease is increasing and it can lead to liver failure. An estimated 170,000 patients die from liver failure each year in Europe alone. During liver failure, an accumulation of protein-bound toxins and increased susceptibility to infection cause multiorgan failure and death. Liver transplantation is the only treatment, but it is limited by organ availability.